FAO World Reference
Laboratory for
Foot-and-Mouth Disease

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  Below are definitions of a number of terms used to classify foot-and-mouth disease viruses
(in preparation)
   
  Serotype
  FMDV serotypes are defined by a lack of cross-protection between viruses. In vitro serological tests (virus neutralisation, complement fixation, ELISA) can be used as a proxy.
  There are seven immunologically distinct FMDV serotypes: O (Oise), A (Allemagne), C, Southern African Territories (SAT) 1, SAT 2, SAT 3 and Asia 1.
  The FAO World Reference Laboratory for FMD uses a colour coding system for each serotype (for labels, maps, etc.): O (red), A (blue), C (green), SAT 1 (yellow), SAT 2 (purple), SAT 3 (orange), Asia 1 (white inside a black circle or sometimes just grey).
   
  Topotype
   
   
   
  Strain
   
   
   
  Genotype
  The term "genotype" can be given to any phylogenetically unique RNA or DNA sequence. However, in the virus world it is often used to indicate a cluster of related organisms. Therefore its meaning is not always easily definable in general terms.